Top 9 Benefits Of Glycine Supplements

Glycine Supplements

Glycine Supplements

Updated on 12/5/2023
Mai DelacruzBy Mai Delacruz
Personal Fitness Trainer & Health Coach
Learn More about Mai Delacruz

What are the benefits of glycine supplements? You can think of glycine as an amino acid that your body uses to make proteins, which are necessary for the growth and maintenance of tissues, as well as the production of a range of compounds like hormones and enzymes that are essential for proper function.

Glycine is an amino acid that may be produced by your body naturally from other amino acids; however, it is also present in foods that are high in protein and is sold as a nutritional supplement.

Besides being a protein component, glycine has many additional beneficial properties for one's health.

Listed below are the top nine applications and benefits of glycine to both health and society regarding its health-enhancing and beneficial effects.

1. Needed To Produce A Powerful Antioxidant

Powerful Antioxidant

Powerful Antioxidant

Glutathione is, without a doubt, a powerful antioxidant that helps to protect your cells from oxidative damage caused by free radicals, which are generally thought to be at the root of many diseases. The amino acid glycine is one of three building blocks that make up glutathione, one of the most important antioxidants in the body. The other two are cysteine and glutamine.

Your body will create less glutathione if you don't get enough glycine, which might affect how well your body manages oxidative stress over time.

In addition, since glutathione levels typically fall with age, ensuring that you eat adequate glycine as you age may help your health.


Your body may produce more of the vital antioxidant glutathione with glycine. Glutathione shields your body from the effects of cell damage.

2. A Component Of Creatine

Component of Creatine

Component of Creatine

As well as being an amino acid, glycine is one of the three amino acids your body needs to produce a substance known as creatine.

Creatine is an amino acid that gives your muscles the energy they need to undertake high-intensity, short-duration activities like weightlifting and running.

It has been shown that taking a creatine supplement and engaging in resistance exercise may enhance the size, strength, and power of muscles.

This supplement is also currently being studied for its potential positive effects on bone health, brain function, and neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, as well as other health issues that might be affected by this supplement other health conditions.

While your body produces creatine on its own, and you may acquire it from the food you eat, consuming too little glycine may cause your body to generate less creatine than it otherwise would.


Besides giving your muscles the energy they need, creatine has also been linked to various other health benefits, such as enhancing the health of your bones and improving your cognitive function when you exercise. Glycine is a component of creatine.

3. Proline, The Principal Amino Acid Found In Collagen

Amino Acid

Amino Acid

Glycine is present in significant quantities in the structural protein known as collagen. Collagen is composed of glycine as every third to fourth amino acid.

Your body stores the most protein overall in the form of collagen, giving your muscles, skin, cartilage, blood, bones, and ligaments the strength they need to function correctly.

In studies, it has been shown that supplementing with collagen supplements improves the health of your skin, reduces joint discomfort, and prevents the loss of bone density as you age.

Suppose you want to maximize your body's ability to produce collagen. In that case, you will need to ensure that you are getting adequate amounts of glycine to increase collagen production in your body.


Collagen is a structural protein that offers several health advantages, including those for your skin, joints, and bones. Among the most abundant sources of glycine, collagen is one of the most significant sources of glycine, and glycine is found in the highest concentration in collagen, making it one of the most abundant sources of amino acid.

4. It Might Help You Get A Better Night's Rest

It is common for people to have trouble getting a whole night's rest because they either have difficulty falling asleep or they have difficulty staying asleep once they do fall asleep.

Consequently, you must remember several things you can do to improve your sleep quality, including avoiding bright displays before bed and avoiding caffeine late at night. It is also possible that glycine may be helpful in this regard.

This amino acid has a sedative impact on the brain and might assist you in falling asleep and staying asleep by reducing the temperature at the center of your body.

Studies conducted on persons who have trouble sleeping have indicated that consuming 3 grams of glycine 30 minutes before bedtime improves sleep quality, shortens the amount of time it takes to fall asleep, reduces the amount of daytime drowsiness experienced, and increases cognitive function.

Because of this, glycine might be a valuable alternative to prescription sleeping drugs for enhancing the quality of sleep experienced at night and reducing feelings of weariness during the day.


The sedative effect of glycine on the brain and its ability to bring down the core body temperature may make it easier for people to fall asleep and have better sleep quality.

5. It May Help Protect Your Liver From The Damage Alcohol Causes

Protect Your Liver

Protect Your Liver

You may be at risk for liver damage if you consume excessive alcohol.

Three primary forms of liver injury are caused by alcohol use.

Fatty liver accumulates fat inside your liver, which causes it to get larger.

Hepatitis caused by alcohol use over a prolonged period and in excess may lead to liver inflammation, known as alcoholic hepatitis.

The last stage of alcoholic liver disease, also known as alcoholic cirrhosis, is characterized by the replacement of scar tissue in the liver due to the destroyed liver cells.

It is interesting to note that research indicates that glycine may minimize the detrimental effects of alcohol on your liver by decreasing inflammation caused by alcohol use.

It has been demonstrated to lower concentrations of alcohol in the blood of alcohol-fed rats by increasing the metabolism of alcohol in the stomach rather than the liver. This avoided the development of fatty liver and alcoholic cirrhosis, both caused by excessive alcohol use.

According to some evidence, glycine may also benefit animals suffering from liver damage caused by excessive alcohol consumption.

Taking glycine may speed up the healing process for mild liver damage caused by alcohol, provided you refrain from drinking alcohol.

A study on rats with alcohol-induced liver damage found that a diet containing glycine for two weeks restored liver cell health 30 percent faster than a control diet. This difference was significant.

The research on the benefits of glycine on alcohol-induced liver damage has only been conducted on animals. Hence the results cannot be extrapolated to humans despite the encouraging findings.


In rats, including glycine in their diets reduces and even reverses the damage alcohol causes to the liver, although the implications of this on people are unclear.

6. May Your Heart Be Safeguarded

Protect Your Heart

Protect Your Heart

There is mounting support for the idea that glycine may reduce the risk of developing cardiovascular disease.

Atherosclerosis, also known as the thickening and constriction of the arteries, may be avoided by preventing the buildup of a chemical that, when present in excessive proportions, has been associated with its development.

This amino acid may also boost your body's capacity to utilize nitric oxide. This significant chemical raises the rate at which blood flows through the body and reduces blood pressure.

Higher glycine levels were related to a decreased incidence of heart disease and heart attacks in observational research that included over 4,100 persons experiencing chest pains. The study followed the participants for 7.4 years.

The researchers found that persons with greater glycine levels had a more favorable blood cholesterol profile. This was the case even after they accounted for the effects of cholesterol-lowering drugs.

In addition, research on rats given a diet rich in sugar revealed that administration of glycine reduced the prevalence of various cardiovascular disease risk factors.

Consuming an excessive amount of added sugar via food and drink may cause a rise in blood pressure, an increase in levels of fat in the blood, and the promotion of harmful fat growth around the abdomen. Any of these factors can cause heart disease.

Although these findings are promising, more clinical research on the impact of glycine on the risk of heart disease in people is required before the supplement may be recommended.


Glycine may reduce the risk factors for cardiovascular disease by avoiding accumulating a molecule linked to cardiovascular disease and by enhancing your body's capacity to utilize nitric oxide.

7. Could Help Individuals Who Have Type 2 Diabetes

Glycine deficiency is a potential complication of type 2 diabetes.

Diabetes mellitus is a disorder that is defined by impaired insulin secretion and action. This means that either your body does not create enough insulin or does not react appropriately to the insulin it produces.

Sugar is absorbed into your cells by insulin, thereby lowering the amount of sugar in your blood.

It is intriguing to note that glycine has been proven to enhance insulin sensitivity in persons who do not have diabetes. It has been hypothesized that taking glycine supplements can improve insulin responsiveness in patients with type 2 diabetes.

Type 2 diabetes is associated with low glycine levels, even when other factors related to diabetes, such as lifestyle, are considered. Despite other risk factors, this remains true.

There is a possibility that those with type 2 diabetes may benefit from taking glycine as a supplement, even if the research is still in its early stages and no definitive conclusions can be drawn from the findings.

You can lower your insulin resistance if you have type 2 diabetes by losing weight through a change in diet and increasing your physical activity level. Losing weight is the best way to lower your insulin resistance.


The diminished insulin activity characteristic of type 2 diabetes may be improved by taking glycine as a dietary supplement. However, there is not enough study on its usage in persons who have the disease for any precise recommendations to be made about its use.

8. May Help Protect Against The Loss Of Muscle

Protect Against Muscle Loss

Protect Against Muscle Loss

According to studies, glycine has been proven to be effective in treating wasting of the muscles, a disease that may be caused by old age, malnutrition, or by a great deal of stress on the body, such as in the case of cancer or severe burns.

The loss of muscle leads to a detrimental decrease in both muscle mass and strength, which in turn leads to a fall in functional status and may worsen other disorders that may be present.

Leucine, an amino acid that substantially slows muscle breakdown and accelerates the development of new power, has been the subject of research as a potential therapy for muscle wasting.

Despite this, the ability of leucine to promote muscle development is hindered by several physiological changes that take place within the body when circumstances exist that cause muscle loss to occur in the body.

It is interesting to note that research conducted on mice with illnesses that cause muscle wasting, such as cancer, has revealed that glycine may promote muscular development, but leucine cannot.

Therefore, glycine shows potential for enhancing health by preventing muscle tissue breakdown that may occur in various situations that lead to a muscular study.

Still, there is a need for more study in people.


Although further study on people is required, preliminary findings suggest that glycine may help retain muscle mass in circumstances that lead to its loss, such as cancer, starvation, and burns.

9. It Is Simple To Incorporate Into Your Diet

glycine in food

glycine in food

Glycine may be found in meat in variable concentrations, and it is particularly abundant in more resilient cuts such as the chuck, round, and brisket.

Glycine may also be obtained from gelatin, a material produced from collagen, and added to various food items to increase their consistency.

Intake of glycine may also be increased in a variety of other, more convenient methods, including:

Include It In Various Meals And Beverages

Glycine is easily accessible and may be purchased as a dietary supplement in either capsules or powder. If you find swallowing tablets difficult, the powder version has a pleasant flavor and dissolves quickly in water.

The term "sweet" is where the name "glycine" originates from in Greek.

Because of its pleasant flavor, glycine powder is effortless to include in one's diet. It may be added to the following foods and drinks:

  • Coffee as well as tea
  • Soups
  • Oatmeal
  • Protein shakes
  • Yogurt
  • Pudding

Take Collagen Supplements

Glycine is the predominant amino acid in the structural protein collagen, which may be found in bone, skin, ligaments, tendons, and cartilage, among other types of connective tissue.

Taking collagen protein supplements is one way that you may increase the amount of glycine that you consume.

It has been shown that the absorption of glycine is less effective when it is taken by itself as opposed to when it is bonded to other amino acids, as is the case with collagen since glycine competes with other amino acids for absorption. Because of this, this is likely to be a more efficient use of resources.

Is It OK To Consume glycine?

Glycine supplementation is risk-free when administered in the recommended doses.

In other studies, participants took up to 90 grams of glycine every day for several weeks without experiencing any severe adverse effects.

As a point of reference, the typical dosage employed in research is between 3 and 5 grams daily.


Glycine powder is widely accessible, and you may include it in some of your favorite dishes and beverages with little effort. In addition to taking collagen supplements, another efficient way to increase your glycine consumption is by taking collagen supplements, both of which are risk-free ways to increase your intake of this essential vitamin.

The Crux Of The Matter



During the past several years, glycine, a type of amino acid, has been found to have a surprising number of positive health benefits.

Glycine is necessary to produce essential molecules in your body, including glutathione, creatine, and collagen.

There is also some evidence that this amino acid may protect your liver from the damage caused by alcohol and increase the quality of your sleep and the health of your heart due to consuming it.

It is also believed that there is some evidence that glycine may help patients suffering from type 2 diabetes and prevent the loss of muscle mass that is associated with illnesses that cause muscle wasting.

You may enhance your consumption of this essential vitamin by consuming certain animal products, adding powdered supplements to meals and beverages, or taking collagen supplements. 

Now, do you know what the benefits of glycine supplements are?

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